目的 研究裸花紫珠(Callicarpa nudiflora Hook.)正丁醇部位的化学成分。方法 利用硅胶、ODS、Sephadex LH-20柱色谱、制备液相色谱等方法进行分离纯化,根据波谱数据分析和文献资料鉴定化合物的结构。结果 从裸花紫珠正丁醇部位分离得到9个化合物,分别鉴定为:6-O-caffeoyl ajugol (1),leucosceptoslde A (2),6-O-咖啡酰-β-D-葡萄糖 (3),nudifloside (4),木犀草素-7-O-葡萄糖苷 (5),槲皮素3′-O-β-D-葡萄糖苷 (6),cistaneside C (7),毛蕊花糖苷(8)和syringalide A 3′-α-L-rhamnopyranoside (9)。结论 化合物1,2,6,7,9为首次从裸花紫珠中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Callicarpa nudiflora. METHODS The chemical constituents were isolated and purified by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their structures were elucidated by spectroscopic evidence and compared with those in literature. RESULTS Nine compounds were isolated and identified as 6-O-caffeoyl ajugol(1), leucosceptoslde A(2), 6-O-caffeoly-β-glucose(3), nudifloside(4), luteolin-7-O-glucoside(5), quercetin 3′-O-β-D-glucoside(6), cistaneside C(7), acteoside(8), and syringalide A 3′-α-L-rhamnopyranoside (9). CONCLUSION Compounds 1, 2, 6, 7, and 9 are isolated from this plant for the first time.
关键词
裸花紫珠 /
马鞭草科 /
6-O-caffeoyl ajugol /
leucosceptoslde A /
槲皮素3′-O-β-D-葡萄糖苷
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Key words
Callicarpa nudiflora Hook. /
Verbenaceae /
6-O-caffeoyl ajugol /
leucosceptoslde A /
quercetin 3′-O-β-D-glucoside
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中图分类号：
R284
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参考文献
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脚注
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基金
国家自然科学基金资助项目(81373955);江西省自然科学基金资助项目(20142BAB205085)
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